Gladstone Institutes

For Julia Kaye, the path to studying neurological disease is deeply personal. Inspired by her mother’s experience with multiple sclerosis, Kaye has dedicated her career to better understanding diseases of the brain—and how science can help uncover new treatments.

Seth Shipman (@seth-shipman.bsky.social ) was recently interviewed for an upcoming documentary exploring where visual art and science intersect. His lab builds molecular tools to study and treat disease—and he was the first to store and reconstruct moving images inside the DNA of living cells.

Nobel Prize-winning scientist Shinya Yamanaka shares the deeply personal and touching story behind the prestigious Ogawa-Yamanaka Stem Cell Prize. Nominations are open for the 2026 prize. Learn more: https://bit.ly/3amoRqH

A new study upends long-held view about how DNA is stored, explaining how subtle shifts in gene activity contribute to cancer, aging, and other complex diseases.

We're currently accepting nominations for the 2026 Ogawa-Yamanaka Stem Cell Prize. In this clip, Deepak Srivastava shares how the Ogawa-Yamanaka Prize has become one of the world's most significant stem cell awards. Learn more about the prize: https://bit.ly/3amoRqH

A new genetic roadmap reveals hundreds of hidden players in #HIV infection, including two proteins that stop HIV in its tracks.

The Ogawa-Yamanaka Stem Cell Prize recognizes individuals whose translational research has advanced cellular reprogramming technology for regenerative medicine. It also celebrates the landmark discovery of iPS cells by Shinya Yamanaka. But what are iPS cells? Learn more 👇

Years before he conducted the research that would earn him a Nobel Prize, Shinya Yamanaka was a postdoctoral scientist at Gladstone Institutes, studying genes. There, he helped discover a gene that’s essential for early embryonic development. Then, the story pauses, until now.

Scientists at Gladstone expanded their retron-based genome editing technology beyond E. coli, showing it works in 15 diverse bacterial species.

Lab experiments can be slow. That's why scientists are turning to AI to speed up the rate of discovery. Researchers are developing novel AI models to predict what goes wrong in disease—and how to fix it.

Check out this highlight reel from Graduate Student Appreciation Week! 🎉 During this week-long celebration, we showcased the milestones and the people behind the science. Grad students: you showed up, you showed out, and we're so glad you're here.

There’s nothing like the excitement of early discovery. Audrey Magsig shares how working with younger mentees reminds her why she loves science—their curiosity, energy, and joy for even the simplest experiments is contagious.

Audrey Magsig, graduate student in the Paz Lab and recipient of the Outstanding Mentoring Award, shares why helping students discover whether science is truly for them is one of the most rewarding parts of her work.

Gladstone researchers are teaming up to tackle this problem.

Go behind the scenes of an on-screen interview with Gladstone scientist Julia Kaye. Julia studies neurodegenerative diseases like ALS, Parkinson’s, and Huntington’s—and collaborates with researchers across the country to analyze the genomes of thousands of ALS patients.

The State of Gladstone is where our community comes together to reflect, connect, and look ahead. Here are some highlights from this year’s gathering.

Postdoc Shyam Jinagal breaks down his research on cardiovascular disease.

Understanding how the heart forms is key to unraveling congenital heart defects. In this video, Gladstone scientist Jon Muncie-Vasic explains how scientists in the Bruneau lab explore the earliest steps of heart development in hopes of finding ways to prevent congenital heart defects.