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A-TANGO Project

@a-tango

🚀 Motivation boost to kick off the new year 🙂: The European Commission agreed to provide a 6-month-long extension to A-TANGO! Let's use this momentum and move forward swiftly now, so that A-TANGO can bring the much-needed G-TAK therapy for severe #AlcoholicHepatitis #cirrhosis #ACLF to the market.

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🤩 Great attendance & active discussion at #EASLCongress today! Very insightful & interactive Networking Session on the evolving definition and #RiskStratification of ACLF, highlighting the new #ATANGOscore & the urgent need for international #Harmonisation of #ACLF criteria. @rajivjalan.bsky.social

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🎬 Summary #movie of A-TANGO's Investigator & Industry Session 🥂 at #EASLCongress. Big thanks to Yaqrit for sponsoring this inspiring event. Let's roll up our sleeves now to start the #GTAK trial in the UK, and hopefully also in India + Germany & other EU countries 🩺 ☺️! #ACLF #cirrhosis #LiverFailure

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Join this exciting event! Don't miss our #OpenInnovation event, uniting experts in #DrugDevelopment, #bioinformatics, and #hepatology. Connect with researchers, industry professionals, and investors to share insights & explore collaboration opportunities! 🚀 Register now: inevent.uk/en/Crowdheli...

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🩺 Who conducted the 1st #ClinicalTrial can be debated, but historical records suggest it happened in biblical times. Cornelius Engelmann (Charité), who supervises A-TANGO's clinical #GTAK trial, held an all-encompassing #Masterclass on Wed, 26 March 2025. #LiverFailure #ACLF #CombinatorialTherapy

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👏 3 more outstanding posters 📣 from the coordinating institute UCL at #EASLCongress 2026 - great job, Supacha & Jinxia! 1️⃣ Ammonia-induced bioenergetic failure via #TLR4🔋 2️⃣ YAQ006 and YAQ005 reduce mortality in #ACLF☠️ 3️⃣ Yaq-001 ameliorates liver injury via gut #microbiome🦠 @rajivjalan.bsky.social

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Let’s talk #inflammation, #alcohol-related #hepatitis and new treatment strategies at #EASLCongress 👉 A-TANGO Networking Session 🗓️ Sat, 10 May 2025, 9:45–10:15 📍 Cirrhosis & Complications Track Hub These short networking sessions are lots of fun! @easlnews.bsky.social #hepatology #cirrhosis #ACLF

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🌟 POSTER THU-182 by Supachaya S. (UCL, @rajivjalan.bsky.social) featured in a #PosterTour at #EASLCongress! 👏 👉 Transcriptomic & metabolic insights into #hyperammonemia: The complementary therapeutic roles of #TLR4 inhibitor (#TAK242) + ornithine phenylacetate 👍 In A-TANGO, we use #TAK242 + G-CSF

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📣 Another top-notch #poster at the very heart of A-TANGO is THU-180-YI by Supachaya Sriphoosanaphan, UCL 👉 #TLR4 inhibition restores cytochrome C oxidase mitigating #hyperammonemia-induced hepatocyte mitochondrial dysfunction #Cirrhosis & Complications #ACLF #LiverFailure @rajivjalan.bsky.social

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