Using vDISCO tissue clearing, and a new ultrabright chemical labeling strategy. This work introduces LINCS for rapid, scalable 3D connectivity mapping from single neurons to whole brains, advances for high-throughput circuit mapping. Great work by Rui Lin lab. www.sciencedirect.com/science/arti...

See our recent @naturebiotech.bsky.social study SCP-Nano in flow! Mapping LNPs, AAVs, and DNA nanostructures to track targeting & unseen toxicity before clinical trials 🤩. Already >190K access, the most in recent years! 👇🏼 www.nature.com/articles/s41...

Additionally, we visualized infiltrating CD68-EGFP immune cells linked to chronic inflammation in obesity on the whole-body scale.

To see how obesity affects the body, we used vDISCO clearing and imaging to visualize the peripheral nervous system in both lean and obese mice.

We developed MouseMapper AI, a deep learning ensemble for the analysis of whole-body systems, including the nervous and immune systems, to map disease/drug perturbations tissue by tissue, organ by organ, at the cellular level in 3D. biorxiv.org/content/10.1...

Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. It reveals obesity-induced changes in facial nerves & body-wide inflammation 👉🧵 biorxiv.org/content/10.1...

Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. It reveals obesity-induced changes in facial nerves & body-wide inflammation 👉🧵https://biorxiv.org/content/10.1101/2024.08.18.608300v1.full.pdf

🧠 Does brain aging always mean vessel loss? We found the opposite in some aged brains: maladaptive hypervascularization, linked to cognitive decline and blood-brain barrier damage. Check it out below! www.biorxiv.org/content/10.6...

We are introducing LipiGo 🤗 A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...

4 ➡️ Main finding 1. DNA handles protruding from LipiGo enabled functional liver detargeting and strong spleen accumulation. Unlike conventional LNPs that mainly go to the liver, LipiGo redirects mRNA delivery to lymphoid organs.

Watch this video for the latest on water main breaks, boil water advisories, water conservation orders and school closings around the Capital Region:

Want to improve the way Sign Language Interpreting services are managed? If you're a Deaf person using these services, our co-operative is THE place for you to have a say and make things work the way YOU want them to ➡️ buff.ly/2V26cKW

Dep. Alencar Santana: "𝙏𝙤𝙙𝙖 𝙫𝙚𝙯 𝙦𝙪𝙚 𝙤 𝙩𝙧𝙖𝙗𝙖𝙡𝙝𝙖𝙙𝙤𝙧 𝙗𝙧𝙖𝙨𝙞𝙡𝙚𝙞𝙧𝙤 𝙚𝙨𝙩á 𝙥𝙧𝙚𝙨𝙩𝙚𝙨 𝙖 𝙖𝙡𝙘𝙖𝙣ç𝙖𝙧 𝙪𝙢𝙖 𝙘𝙤𝙣𝙦𝙪𝙞𝙨𝙩𝙖, 𝙤𝙨 𝙥𝙖𝙩𝙧õ𝙚𝙨 𝙚𝙨𝙥𝙖𝙡𝙝𝙖𝙢 𝙖 𝙢𝙚𝙨𝙢𝙖 𝙢𝙚𝙣𝙩𝙞𝙧𝙖 𝙥𝙖𝙧𝙖 𝙞𝙢𝙥𝙚𝙙𝙞𝙧 𝙖 𝙫𝙞𝙩ó𝙧𝙞𝙖: “𝙊 𝘽𝙧𝙖𝙨𝙞𝙡 𝙫𝙖𝙞 𝙦𝙪𝙚𝙗𝙧𝙖𝙧!” - 𝘾𝙇𝙏 - 𝙎𝙖𝙡á𝙧𝙞𝙤 𝙢í𝙣𝙞𝙢𝙤 - 𝙁é𝙧𝙞𝙖𝙨 - 𝟭𝟯° 𝙨𝙖𝙡á𝙧𝙞𝙤 𝙚 𝙤𝙪𝙩𝙧𝙤𝙨... É 𝙨𝙚𝙢𝙥𝙧𝙚 𝙖 𝙢𝙚𝙨𝙢𝙖 𝙡𝙖𝙙𝙖𝙞𝙣𝙝𝙖! 𝙉ã𝙤 𝙘𝙖𝙞𝙖 𝙣𝙚𝙨𝙨𝙖 𝙘𝙤𝙣𝙫𝙚𝙧𝙨𝙖!"

🎵I Want My Flag Back - Saturday, May 9, 2026 part 1 Flag Wave Washington state - Tommy and his minions Music: I Want My Flag Back by The Resistance Full song at www.youtube.com/watch?v=mleW... #filk #protests #ice #pdx

📌 On February 5, Governor Macklem will deliver a speech before the Empire Club of Canada. More details: https://bit.ly/45LOQ9U #cdnecon #economy

What skills is @savethechildren.org US looking for? At a recent career event, Douglas Mercer, Managing Director of Talent Attraction and Acquisition at Save the Children US, highlighted the specific roles the organization is currently seeking to fill. #careers #globaldevelopment #SaveTheChildren

🚨 ESDEEKID's FORTNITE EMOTE 🚨 [ Via HYPEX ]

The spiral will try to pull you outward. It will flash headlines. It will trigger outrage. It will tempt your nervous system to spin. But power is not found in reactivity. Power is found in regulation. You are more powerful when calm than when… #SolarSage #NervousSystemRegulation #CollectiveEnergy

Kash Patel is "noivous in da soyvous".

Genuinely what was the thought process behind making it to where you have to stop shooting to recharge your shield

What if... for Otakon... we also had some Anitunes, city pop, and more to play at the Museum over the weekend as well? 👀

The Ukrainian unmanned systems unit “Chornyi Lis” destroyed a Russian occupiers 5N63S command post (which serves the S-300 surface-to-air missile system and is equipped with a radar) on one of the directions, using loitering munitions.

It's SHOWTIME! #AEWDoN ➡️ allelitewrestling.com/aewonppv

So that you know …

“he is disgusting, he is despicable, the guy is a lying cheating pig” Most of you know who he 👇 is talking about before even listening

🚨🚨🚨ICE PEPPER SPRAYED A UNITED STATES SENATOR‼️

The court that almost overturned votes for Trump looks very different now.

The right can’t attack Texas Senate candidate James Talarico on his policies, so they’re trying to distract voters with a culture war.

Dorchester’s Taina Mair represents the very best of Boston. Congratulations Taina on being a first round WNBA pick by the Seattle Storm! ⛈️💚

Draymond trolling Kenny 😂

Making fun of Jazz like this is crazy! #jazz, #music, #freepalestine

#cf97 goal of the day for May 4, 2026: September 30, 2025 - MLS Inter Miami CF 3-5 Chicago Fire - Justin Reynolds 80'

Does AI always generate bad code? Not so fast! This week on the Shared Security Podcast, we discuss how over a million messages and thousands of ID photos were leaked due to poor coding practices. Watch and listen to the full discussion wherever you like to get your podcasts. Links in 🧵below!

Simple sentences hit different. - Valerie F. 🗣️ #linguistics #simpletalk #ValerieFridland

This next election vote for the party fighting fraud not the one covering it up. Vote Republican! See more of NEWSMAX:  https://www.newsmax.com/

The view from inside Integrity as recovery forces pop open the hatch Credit: Reid Wiseman #Artemis

🚨LIVE‼️Saturday at 5:05PM CT 💫Join the #AEWCollision & #MLWFusion 💥Live Reaction & Review @dedrian91.bsky.social : www.youtube.com/live/LMGtU6s... #aew #mlw #hazuki #stardom

📊 2026-05-31 • Gaza War: Israeli Strike Kills Palestinian Doctor in Gaza as Conflict Enters Day 962 • Ukraine War: Ukraine Drones Strike Volgograd Lukoil Refinery; Sweden Donates 16 Gripen Jets in $2.7B Package; Russia Escalates to 267 Attacks and 269 Guided Bombs • Recession Ri… 🔗 watchboard.dev

What would your teeth say if they could talk to you? Maybe they are trying to tell you something? Are you ignoring them? Let' talk about it. join oral health coach LeighGS 7pm Facebook Live.

#ai #jobs #explore #fyp #BreakingNewsUSA Full story: https://jqjo.com/2026-05-11/us/Business/fr/bs/L'IA-supprime-des-milliers-d'emplois-;-le-vôtre-est-il-menacé/1272580

Playing by ear is a real talent!

THE UNION TIED?

St. Paul is an incredible place, and the home of our second One City One Take. The concept is simple: One very long unbroken take exploring the city. You can either watch it all at once, or skip around using chapter markers. I hope you enjoy.

50 Years Ago Today: An epic bench-clearing brawl breaks out between the #RedSox and #Yankees at Yankee Stadium after Lou Piniella collides with catcher Carlton Fisk! Bill Lee separates his left shoulder in the ensuing skirmish! (May 20, 1976) #OldSchool #MLB #Baseball #History

🎒 What if healing your cold sore wasn't even a thing you had to keep thinking about? Dynamiclear Rapid makes it simple: apply it once and that's it. No hassle of carrying a tube everywhere, reapplying after meals or before bed. 👌 Find us on Amazon, or at your local pharmacy!

📅 A busy week doesn’t leave room for cold sores. When the first tingle hits, Dynamiclear Rapid is a #ONEANDDONE solution. Hit it once, and move on. No reapplying needed! Find us on Amazon, or at your local pharmacy! #ONEANDDONE #DynamiclearRapid #ColdSoreRelief

Yea I can definitely see that 😂 #adulting #lgbtqia #mtf #ftm #foryoupage

At airport lounge waiting for Beijing flight and there is a robot drinks tray because of course there is... #china #hongkong

G Herbo’s fiancée Tiana Williams slams realistic toy gun gift for her son, citing safety fears and parenting boundaries. Sparks online debate on child gun play. #GHerbo #TianaWilliams #ParentingDebate #ToyGunSafety #ViralNews 🔗 Learn more inside – www.hypefresh.com/g-herbos-fia...

Der Herr Mini ist gestern in den Regen gekommen. 🐿️💦💦💦🥹 #squirrels #balkonhörnchen #eichhörnchen

I Do #wedding #dress #bride #video #shorts #clip

When a husky becomes a vampire, a tale of loyalty, love, and revenge unfolds. https://www.amazon.com/Snow-Blood-Vampire-Mystery-Thiller-ebook/dp/B00JOWG05O #SnowBlood #CarolMcKibben #FangedFury #OtherworldlyUnion

DoN2026 in NY thread

🚨Ralph Norman has picked a running mate. Learn about the "Freedom Caucus Ticket" and what this late breaking announcement really tells us. Hint: It's a reminder to everyone just how consequential this election is — Democrats, Independents, and Republicans, make sure to VOTE!🇺🇸

Kim Seon Ho is being his playful self during the "What's in the Box" challenge during the Love Factory fan meet in Manila! His adorable "gulat" reaction had everyone laughing! 🩵 @ovationprod #김선호 #KIMSEONHO #LOVE_FACTORY #LOVE_FACTORY_ASIATOUR #KimSeonHoInManila2026

🇺🇦 Ukrainian kamikaze drones struck Saint Petersburg, targeting a central oil depot and port infrastructure. Several large fuel storage tanks were set ablaze and are still burning at this time.

Timeline cleanse.

We should Hire an attorney for a class action lawsuit for mental anguish depression anxiety, & Just do what Donald does Sue him for 10 billion dollars, & settle out of court, for him & his crime syndicate gotta either leave USA for life or it's prison, SINCERELY the RADICAL LEFT Scum 🥰👇

Why do we even try