To see how obesity affects the body, we used vDISCO clearing and imaging to visualize the peripheral nervous system in both lean and obese mice.

Today in Nature, we report MouseMapper: foundation-model AI to map disease perturbations across the entire mouse body cell-by-cell. In obesity, it revealed body-wide inflammation & unexpected facial nerve damage. www.nature.com/articles/s41... More at: x.com/erturklab/st...

Our Nature Biotech paper hit 225K+ accesses in 3 months! 🤩 7 first authors from computer science, biology & chemistry prove that great science is teamwork. We combined AI & imaging to visualize single cells across whole organisms. Team synergy > individual brilliance. www.nature.com/articles/s41...

Our new study shows that SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving long COVID. mRNA vaccines help but cannot stop it🔬🧠🦠🧵Your weekend read👇 @cellpress.bsky.social cell.com/cell-host-mi...

Our recent work in @Nature, MouseMapper uses foundation-model AI, mapping perturbations in mouse body cell-by-cell, revealed unexpected facial nerve damage. Proud to see >75K accesses & >60 news stories in the first week. Paper->> www.nature.com/articles/s41... Next www.biorxiv.org/content/10.6...

Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. It reveals obesity-induced changes in facial nerves & body-wide inflammation 👉🧵https://biorxiv.org/content/10.1101/2024.08.18.608300v1.full.pdf

See our recent @naturebiotech.bsky.social study SCP-Nano in flow! Mapping LNPs, AAVs, and DNA nanostructures to track targeting & unseen toxicity before clinical trials 🤩. Already >190K access, the most in recent years! 👇🏼 www.nature.com/articles/s41...

4 ➡️ Main finding 1. DNA handles protruding from LipiGo enabled functional liver detargeting and strong spleen accumulation. Unlike conventional LNPs that mainly go to the liver, LipiGo redirects mRNA delivery to lymphoid organs.

We discovered that the skull bone marrow has direct connections to the brain surface & mirrors brain inflammation, making it a new site for diagnosing & monitoring brain pathologies. Kolabas…Ertürk, Cell (2023): www.cell.com/cell/pdf/S00... Our Tech: www.biorxiv.org/content/10.1... bit.ly/3PQuymm

7) 🧩 Main finding 4. Plug-and-play targeting: LipiGo’s DNA handles act as modular building blocks. Conjugating a white adipocyte–specific aptamer enabled tissue-specific mRNA delivery with enhanced uptake in white adipocytes 🎯

INSIDE-THE-PARK GRAND SLAM 🤯 JAMES WOOD JUST DID THAT 🔥 (via @MLB)

WE HAVE A TIE! Today you can vote for the Jets or The Steelers, whose gone? #NFL #Pittsburgh #Steelers #newyorkjets #NewYork

Leonardo da Vinci TED Talk “On Creativity”

Golden League Eleven 2026 – Jornada 4 Duelo en la Federación Malagueña: La Golderoneta F.C. vs Eurogeta. Clip 1: paradón de Oliver ante el disparo de Manu. Clip 2: “postidato” de nuestro narrador @alepostigo.bsky.social sobre el club sudafricano Mamelodi Sundowns F.C. 📅 30/01/2026 – 22h

"Honestly, it's something I had to learn early on in my college experience. " Offensive guard Fernando Carmona speaks on where he developed his "Brawler" mentality and how it can help him in the NFL with the Tennessee Titans. #titans #nfl #titanup #nfldraft

‘Good Russians’ do exist. They either: 
A) admit that all adult Russians bear responsibility for the war 
B) fight for Ukraine 
C) all of the above ‘I would say that all Russians are to blame for this war.’ — ‘Caesar,’ one of the commanders of the ‘Freedom of Russia’ Legion

A remote rural town makes headlines as it goes up for sale. But behind the novelty lies a rich family legacy. That’s #CarteBlanche this Sunday at 7pm on M-Net channel 101, and DStv Stream. #SouthAfrica #News

#fragments77 Fractal №1 #wgsl #webgpu #tsl #threejs #shader

Ich schwöre sonst bin ich viel besser🤣 #gaming #Fortnite #germangirl🇩🇪 #KathyClips #BattleRoyale #viral #randomsquad

January 6 was a constitutional crisis that continues. The mob stopped the count, terrorized Congress, and left one dangerous question behind. Who paid for it? Listen: https://loom.ly/REdODrI #oligarchy #dictatorship #dictatortrump

1 of 2 Newark, NJ Delaney Hall: Protesters are outside the facility demanding the release of Martin Soto, the leader that started a hunger & labor strike to protest inhumane conditions. ICE is trying to transfer Martin+ to a different facility; there is no transfer order. @cnn.com @reuters.com

🔴RED FLAG🔴 Collet out of the race with 8 laps to go after a huge hit on the right side! #Indycar #Indy500

With Wemby ejected from Game 4, San Antonio missed out on a chance to seize control of its series with Minnesota. For Game 5 tonight, the Spurs know what they need to regain the series lead. “We need an upset Vic.” bit.ly/3PgySQ4

Ashley St. Clair, the former MAGA influencer and ex-girlfriend of Elon Musk, is now exposing what she says is the truth behind the MAGA influencer machine.

LET’S TALK RECORDS! No. 90 (Redux): LET IT BE by THE REPLACEMENTS Part 2 #letstalkrecords #thereplacements #letitbe #collegerock #punk #punkrock #alternative #alternativerock #vinyl #vinylcollection #vinylcollector #vinylcommunity #vinylrecords #music

The idea that girls do not enjoy maths and physics is outdated. In this clip, I’m joined by Sarah Eggleston, Founder of fflow and former IBM engineer, challenging common myths around women in STEM. Talent is not gendered. Interest is not fixed. Opportunity shapes confidence. 1/3

❗️🇷🇺🇨🇳 putin is in China right now on his two-day visit and is bragging to Xi Jinping that Russia is a “reliable supplier of energy resources to China”. #China #Russia #putin #XiJinping

The “imminent threat” argument for striking Iran does not hold up. The administration cannot even keep its story straight about why the attack happened. When the explanation keeps changing, it usually means there was no real justification.

A hit and run according to OP who said he heard but didn't see it. West Hollywood. OP: tiktok.notzapata

JOSEPH BEUYS - FELT TV 1970 Fluxus the only Beuys action executed specifically for the camera. It opens with Beuys seated in front of a TV set showing a program which is invisible because the screen is covered by felt. The boxing-gloves used later in the action lie at the ready beneath his chair.

Kyle Kulinski points out a terrifying shift: AI is destroying our shared reality. Kyle explains we are entering a dystopian landscape where objective truth is constantly debated, forcing us to over-analyze everything. Are we losing our grip on facts? 🤖📉

Protest in Lawrence, Kansas last Sunday. #Resist #Protest #LFK

Now imagine that’s your child separated from her loved ones. She’s braver, more mature, and intelligent than this entire administration!

There is no reason the military should be at our polls. Period. When I asked, Secretary Hegseth wouldn’t answer directly. That’s because he knows President Trump is watching and doesn’t want to make him angry.

Sigh ... obligatory hashtags ... #PrecautionaryPrincipleFFS #PreventionBetterThanCure #Wear≥FFP2RespiratorsNotMasks #NoFalseEquivalence #NameAndNormalise ... and just supply them ... OK? And show them this 1:19 video ...

Endymion Ball Finale Katy Perry performs. 2nd clip

The Boy Who Became England’s Greatest Knight From unwanted hostage to Regent of England, this is the unbelievable story of the greatest knight who ever lived. #history #europehistory🇪🇺 #england #warhistory🇺🇸 #medieval #historytime #historyfacts

Today, at the side event of the United Nations Human Rights Council in Geneva, I made it clear: Russia is desperate to damage Europe. Its operations in Africa are hybrid warfare aimed at fueling instability, driving migration flows northward & weakening EU unity. Europe must act!

Source #Japan #Nippon

Biggest Myth With Safety!  Share Your Thoughts   LS Tip - Neg Results

#chipmunk Time for a slightly late lunch....

2 Congressman Maxwell Alejandro Frost @RepMaxwellFrost ‼️UPDATE: I just got out of “ #AlligatorAlcatraz.” Here’s what I learned about the facility closing: 2/3

"Republicans know this is a loser." Joel Payne and @stephruhle.bsky.social dig into the politics of the Iran war on the #Nightcap after Pete Hegseth faced some tough questions from both Democrats and Republicans on Capitol Hill.

It's DAY 2 of the annual subathon and we only have 9 hours left on the clock! I plan on clocking in AT LEAST a 12 hour day today so you GOTTA raise this timer! YCH of your character at 20 subs, GUARANTEED LEGENDARY PULL in Mutt set at 50 subs, and so much more! MAKE TIMER GO UP! twitch.tv/cassmutt

HEINE HEINE HEINE HEINE HEINE HEINE HEINE HEINE MAN

Justice will prevail 💪✊🇬🇪 today we protest near special Investigation service and state security service #Tbilisiprotests #GeorgiaProtests

Cuthbert with the finish. 🎯🏴󠁧󠁢󠁳󠁣󠁴󠁿 #CFC / #W7F

Our latest tutorial by Matis Dené explores a scroll-driven, infinitely looping 3D image tube built with React Three Fiber. You'll learn shader-based deformation, inertial motion, seamless looping, and how to sync DOM and WebGL into one cohesive motion system: tympanus.net/codrops/?p=1...

Crip run Begin slow Wind down

The babies you save in the dungeon will show up in the class room/hub #Nintendo #tinybabycrowngames #indiegame #gamedev #xbox #ゲーム制作 #nintendo #steam #rpg #toon #madewithunity #dungeoncrawler #gaming

Episode 25 of Total Nileation, the podcast that brings you the good news they don’t report is out now! Available wherever you get your podcasts. 🦎 Lizards can regrow tails. Starfish can regrow arms. Axolotls can regrow basically anything. Mammals? Not so much… until now. 📎 Sources: Ars Technica

Whatever your opinion on Brexit is, I don't think it should be controversial to say that in order to re-join the EU, there should be consent of the people.

June 1 – Pride Month begins Trivia: Honors the 1969 Stonewall uprising.

🇵🇭🇯🇵 Leaders Sing "Imagine" Together For daily global news videos, please visit Ranked.News/videos

Peyote vs other hallucinogens: lsd, psilocybin, and mescaline compared 🔄 #peyote https://go.casadechiles.com/peyote-bluesky

Oz: “If you haven’t filed a claim, your coverage might be fraud.” Sir, that’s called “being healthy.” Please stop letting TV doctors run policy. #aca #medicareforall

A wet morning but heaviest rain clearing Northeast now with a mix of sunny spells and scattered heavy showers to follow.

Air Quality Alert issued June 4 at 3:15PM EDT by NWS Upton NY the new york state department of environmental conservation has issued an air quality health advisory for the following counties: new york, bronx, kings, queens, richmond, nassau, (1/6)

"Was die durchgeknallte Trulla nicht sagt: Ihr Netzpaket sorgt dafür, dass in der Hälfte des Landes keine Solar und Wind Anlagen mehr gebaut werden, weil aus Angst vor teuren Abschaltung keiner mehr investiert. Weswegen gerade die 16 Energieminister mit 16 zu 0 Stimmen ihre Politik abgelehnt haben."

World Environment Day is a reminder that climate action is not only about what we reduce. It is also about what we restore. Habitats. Pollinators. Soil. Green spaces. Curiosity. Care. Nature is the system holding the whole thing together. 🐝🌍 #WorldEnvironmentDay #NowForClimate