Ali Maximilian Erturk
@erturklab
4 ➡️ Main finding 1. DNA handles protruding from LipiGo enabled functional liver detargeting and strong spleen accumulation. Unlike conventional LNPs that mainly go to the liver, LipiGo redirects mRNA delivery to lymphoid organs.
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More from Ali Maximilian Erturk
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Our new study shows that SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving lon...
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Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. It reveals obesity-indu...
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We developed MouseMapper AI, a deep learning ensemble for the analysis of whole-body systems, including the nervous and immune systems, to map disease/drug perturbations tissue by...
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See our recent @naturebiotech.bsky.social study SCP-Nano in flow! Mapping LNPs, AAVs, and DNA nanostructures to track targeting & unseen toxicity before clinical trials 🤩. Already...
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Today in Nature, we report MouseMapper: foundation-model AI to map disease perturbations across the entire mouse body cell-by-cell. In obesity, it revealed body-wide inflammation &...
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Excited to share our latest work with Denali Therapeutics as Deep Piction. Using our proprietary clearing & imaging, we’ve mapped the full targeting profile of brain-penetrating transport vehicles (ATVs) in both whole mouse bodies and monkey brains. nature.com/articles/s41...
We discovered that the skull bone marrow has direct connections to the brain surface & mirrors brain inflammation, making it a new site for diagnosing & monitoring brain pathologies. Kolabas…Ertürk, Cell (2023): www.cell.com/cell/pdf/S00... Our Tech: www.biorxiv.org/content/10.1... bit.ly/3PQuymm
Additionally, we visualized infiltrating CD68-EGFP immune cells linked to chronic inflammation in obesity on the whole-body scale.
Our recent work in @Nature, MouseMapper uses foundation-model AI, mapping perturbations in mouse body cell-by-cell, revealed unexpected facial nerve damage. Proud to see >75K accesses & >60 news stories in the first week. Paper->> www.nature.com/articles/s41... Next www.biorxiv.org/content/10.6...
Our new study shows that SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving long COVID. mRNA vaccines help but cannot stop it🔬🧠🦠🧵Your weekend read👇 @cellpress.bsky.social cell.com/cell-host-mi...
See our recent @naturebiotech.bsky.social study SCP-Nano in flow! Mapping LNPs, AAVs, and DNA nanostructures to track targeting & unseen toxicity before clinical trials 🤩. Already >190K access, the most in recent years! 👇🏼 www.nature.com/articles/s41...
We developed MouseMapper AI, a deep learning ensemble for the analysis of whole-body systems, including the nervous and immune systems, to map disease/drug perturbations tissue by tissue, organ by organ, at the cellular level in 3D. biorxiv.org/content/10.1...
We are introducing LipiGo 🤗 A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...
Our Nature Biotech paper hit 225K+ accesses in 3 months! 🤩 7 first authors from computer science, biology & chemistry prove that great science is teamwork. We combined AI & imaging to visualize single cells across whole organisms. Team synergy > individual brilliance. www.nature.com/articles/s41...
7) 🧩 Main finding 4. Plug-and-play targeting: LipiGo’s DNA handles act as modular building blocks. Conjugating a white adipocyte–specific aptamer enabled tissue-specific mRNA delivery with enhanced uptake in white adipocytes 🎯
STRANDED IN THE CONCRETE JUNGLE is image no. 102 from "Of MICE and MONUMENTS". For more info check: linktr.ee/StefanRoloff RedOrchestraNFT.com #nftart #nftartist #nftcommunity #redorchestra #monument
Proud to share our second TV ad! My mom’s battle is a story far too many families can relate to. No one should have to lose the care they need because they can’t afford insurance. I’m fighting for Medicare for All. If you’re ready to support that vision, I’d be honored to have your vote on June 2.
Last week our Chief Exec @dannetts.bsky.social explained how ISM members' experiences with GenAI kickstarted Brave New World? and shared the impact its had since it was launched in January . Read the report and write to your MP - we need #JusticeForCreators: www.ism.org/brave-new-wo...
Scott Bessent says Trump’s tax cuts are showing early results, with 60M+ returns claiming deductions and 5.5M TrumpAccounts opened. The plan aims to boost take-home pay and savings for families. #Trending #news #ScottBessent #trump #reels
Grocery costs just jumped 3%, and it is only getting worse. Trump is hiking diesel prices with his reckless Iran conflict, and we are the ones stuck with the bill. We are literally paying for a war we never wanted. 💸 #WeCantAffordTrump
This just happened at Parliament House, Canberra. Activists sent a message to Prime Minister AlboMP and Foreign Minister SenatorWong that they need to meet with the gbsumudflotilla activists and believe them, not the Israelis. Activists silently stayed in the stress position until removed by police
Pushing back against Republican efforts to usher in a new Jim Crow era is a new civil rights movement, with leaders such as Democrat TN State Representative Justin J Pearson offering hope. Join @thelisagraves and I as we go LIVE next Monday night at 5pmET on @legalafmtn.bsky.social YouTube.
Our Friday will be a bit warmer than our Thursday. Plus, we have some concerns about wildfire conditions this afternoon. Here is a quick update as we head towards our weekend.
We weren’t the same people we used to be and that’s what made it work. This song’s about healing, forgiveness, and finding each other again. #indierock #emotional #inspirationalmusic #musicthatmatters
Fed leadership drives headlines, but fundamentals drive results. Read our blog for market impact insights. Link in comments. #FedLeadership #MarketImpact #LongTermInvesting #InvestmentStrategy #FinancialEducation #MarketFundamentals #EconomicInsights #WealthBuilding #SanDiego #California
"We Need To Address Stigma When Accessing Services..." | Listen UP Episode 7 - Marc Buchanan - Now Live! In Listen UP Episode 7, Marc Buchanan shares how stigma‑free services can speed the first steps into recovery. EPISODE 7 - LISTEN NOW - lk2.app/luep7 #seeksupport #addictionrecovery
Colbert Fans know a fake hero and fix it with fake Ai video. Remember our motto: “Humor Heals” #Colbert #USDemocracy
Speaking to reporters in Ottawa, PM Carney comments on reports that Steven Guilbeault is set to announce his resignation as MP later in the day. “I’m sure in some way, shape or form, we’ll have an opportunity to continue to work together on issues of interest,” he says. #cdnpoli
Markwayne Mullin: "If CBP isn't there processing international flights, then those individuals when the airlines land won't be permitted into the United States. If things don't change, we're gonna have to make this step pretty quick."
We’re ONE WEEK away here’s a little checklist to make sure you’re ready: Event Countdown Checklist • ☐ ❄️ Grab Your Ticket • ☐ ❄️ Plan Your Outfit • ☐ ❄️ Mark Your Calendar • ☐ ❄️ Charge Your Phone/Cameras • ☐ ❄️ Invite a Friend or Two if you have not RSVP'ed click here - https://loom.ly/LD5IzqA
Japan's RIKEN Institute developed a strong, recyclable plastic that dissolves in seawater—no microplastics. In soil, it breaks down in just 10 days & even releases natural fertilizer! designboom.com/technology/researchers-develop-recyclable-plastic-fully-dissolves-sea-riken-center-03-11-2025/
Registrations for #ThePMAs Creator of the Year 2025 are now open! Know someone inspiring the community or think it could be YOU? Step forward and shine! For more on how to enter, click the link in our bio. Registration closes May 4th. photomodeawards.com
🔦 This week’s #PANCAIDPartnerSpotlight: KSM Innovation / MACCABI KSM's strengths are: 📊 Access to 30+yrs of digital health data from 2.7M members 🧬 900K biobank samples In PANCAID, they contribute to WP1 by providing blood samples #HealthData #CancerDetection #Biobank
"Why do they keep killing children?! They should stop a war the second a single child gets a scratch! What kind of cowardice is this?
Friday is #WorldCircusDay so for the Diner on 91.9 WFPK I want you to give me songs that reference any aspect of a circus or carnival IN THE TITLE. (1 x person PLEASE!) Listen for yours starting tomorrow morning at 8 on 91.9 WFPK, lpm.org or the Louisville Public Media app. 🎪🤡
Right now, the conversation isn’t about nuclear programs, or free and fair elections in Iran. It's about reopening a body of water that was open before this war started. Chalk that up as a win for Tehran.
Candles. You know. For doing it • Marbles on Stream #VTuber #ENVTuber #VSky
Trump really likes the Rush Hour movies. Here’s how he just turned the next one into a bribe for a massive merger.
ABS overturned in #Phillies at #Dodgers (Bot 1). J.T. Realmuto challenged the ball call on Andrew Painter's pitch to Freddie Freeman. Ball -> Called Strike. HP: Sean Barber | Upheld 45.9% (28/61). Result: Freddie Freeman called out on strikes.
Fact Check: FAKE Quote By Muslim Man Saying 'Christians, You're No Longer Allowed To Say 'Merry Christmas'' #CheckTok #MerryChristmas #AIgenerated #FactCheck #MuslimCommunity leadstories.com/hoax-alert/2...
SLING NEWS Dr. BUTCH WARE GREEN PARTY CANDIDATE, 2026 CALIFORNIA GUBERNATORIAL RACE FULL INTERVIEW: THURSDAY. APRIL 23, 2026. 3PM (PACIFIC TIME)
❗️🇺🇦Ukrainian servicemen from the 422nd Separate Unmanned Systems Regiment “Luftwaffe” are destroying 🇷🇺Russian logistics in the deep rear, more than 70 km from the line of contact.
Enabot EBO SE FamilyBot Home Camera Robot: 1080P Movable Pet Camera Indoor, Battery-Operated, Auto-Recharge, Night Vision, 2-Way Talk, Local Storage, APP Control 🛒 Check on Amazon: https://www.amazon.com/dp/B09R6V3CJM/?tag=sersart2024-20
Kim Seon Ho is being his playful self during the "What's in the Box" challenge during the Love Factory fan meet in Manila! His adorable "gulat" reaction had everyone laughing! 🩵 @ovationprod #김선호 #KIMSEONHO #LOVE_FACTORY #LOVE_FACTORY_ASIATOUR #KimSeonHoInManila2026
you post once, we blast it to 12+ platforms wake up to your content thriving. #socialmediaautomation #contentcreators