Ali Maximilian Erturk
@erturklab
Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. It reveals obesity-induced changes in facial nerves & body-wide inflammation 👉🧵https://biorxiv.org/content/10.1101/2024.08.18.608300v1.full.pdf
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More from Ali Maximilian Erturk
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Our new study shows that SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving lon...
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We developed MouseMapper AI, a deep learning ensemble for the analysis of whole-body systems, including the nervous and immune systems, to map disease/drug perturbations tissue by...
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See our recent @naturebiotech.bsky.social study SCP-Nano in flow! Mapping LNPs, AAVs, and DNA nanostructures to track targeting & unseen toxicity before clinical trials 🤩. Already...
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Today in Nature, we report MouseMapper: foundation-model AI to map disease perturbations across the entire mouse body cell-by-cell. In obesity, it revealed body-wide inflammation &...
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Our recent work in @Nature, MouseMapper uses foundation-model AI, mapping perturbations in mouse body cell-by-cell, revealed unexpected facial nerve damage. Proud to see >75K acces...
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To see how obesity affects the body, we used vDISCO clearing and imaging to visualize the peripheral nervous system in both lean and obese mice.
Excited to share our latest work with Denali Therapeutics as Deep Piction. Using our proprietary clearing & imaging, we’ve mapped the full targeting profile of brain-penetrating transport vehicles (ATVs) in both whole mouse bodies and monkey brains. nature.com/articles/s41...
🧠 Does brain aging always mean vessel loss? We found the opposite in some aged brains: maladaptive hypervascularization, linked to cognitive decline and blood-brain barrier damage. Check it out below! www.biorxiv.org/content/10.6...
7) 🧩 Main finding 4. Plug-and-play targeting: LipiGo’s DNA handles act as modular building blocks. Conjugating a white adipocyte–specific aptamer enabled tissue-specific mRNA delivery with enhanced uptake in white adipocytes 🎯
Today in Nature, we report MouseMapper: foundation-model AI to map disease perturbations across the entire mouse body cell-by-cell. In obesity, it revealed body-wide inflammation & unexpected facial nerve damage. www.nature.com/articles/s41... More at: x.com/erturklab/st...
4 ➡️ Main finding 1. DNA handles protruding from LipiGo enabled functional liver detargeting and strong spleen accumulation. Unlike conventional LNPs that mainly go to the liver, LipiGo redirects mRNA delivery to lymphoid organs.
Our new study shows that SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving long COVID. mRNA vaccines help but cannot stop it🔬🧠🦠🧵Your weekend read👇 @cellpress.bsky.social cell.com/cell-host-mi...
Additionally, we visualized infiltrating CD68-EGFP immune cells linked to chronic inflammation in obesity on the whole-body scale.
See our recent @naturebiotech.bsky.social study SCP-Nano in flow! Mapping LNPs, AAVs, and DNA nanostructures to track targeting & unseen toxicity before clinical trials 🤩. Already >190K access, the most in recent years! 👇🏼 www.nature.com/articles/s41...
We discovered that the skull bone marrow has direct connections to the brain surface & mirrors brain inflammation, making it a new site for diagnosing & monitoring brain pathologies. Kolabas…Ertürk, Cell (2023): www.cell.com/cell/pdf/S00... Our Tech: www.biorxiv.org/content/10.1... bit.ly/3PQuymm
“Let me in! Let me in! March Mammal Madness has started and I need your laptop!!!” #2026MMM
Sun rising over Ocean City NJ - Thursday May 21 2026 #OceanCityNJ #Sunrise #BeachLife #NewJersey #NatureLovers #MorningViews
📣 Success for the first Equity and Exchange Event! Congratulations to the four award-winning presenters! *** 📣 Une journée de l’équité, de la diversité et de l’inclusion couronnée de succès! Félicitations aux 4 présentateurs récompensés ! douglas.research.mcgill.ca/news/a-succe...
🚨 Crimes de guerre russes Ils jettent les gens à la rue. À Marioupol, les occupants russes obligent les résidents à quitter leurs appartements et apposent des avis d'expulsion sur les portes pour avoir refusé d'obtenir le passeport russe.
Happy New Year! We're grateful for our community's support as we work together to end homelessness. This year, let's continue to build a stronger Central Ohio for all. CSB is closed Jan. 1-2. We'll be back Jan. 5. Call the Homeless Hotline at 614-274-7000, open 24/7, for help.
Here's Eco-Cat 🐱 with some positive news about #sustainability achievements in the business world. 🌍 Read more: sustainabilityonline.net/news/multile... ✅
Trump's Reflecting Pool repairs now cost $13.1 million. His handpicked contractor was originally supposed to do it for $1.8 million.
We want to hear what leaseholders think of the Government's plans for commonhold and leasehold reform. Help us decide what changes to recommend to the Government to improve the draft Bill, as @florenceeshalomi.bsky.social explains. Take our survey by 31 March: https://forms.office.com/e/Hj27jXurmA
Prevent Grip Failure During Heavy Lifts Using Towel Hangs #fitness #fitnesstips #workout #health #gym #exercise
HerCourtVision: Why Tiffany Hayes Got So Furious After Caitlin Clark’s Fast-Break Logo Bomb! #CC22 #CaitlinClark #FeverRising #NowYouKnow #FromAnywhere #IndianaFever #WNBA
📵 Putin, like any good dictator, “protects” Moscow by shutting down the Internet for over a week! No bad news, no protests… just $70M in business losses. 👍 You don’t cut Internet if everything’s fine. Putin fears the truth—and the collapse is starting. 👀 #StandWithUkraine #MakeRussiaSmallAgain 🇺🇦
Not very good at Invincible VS, but I’m definitely learning. A couple of choice moments from online 🥹
📣 Tomorrow, the 19th of November, the #SettleAdvocates are going to be in parliament meeting with MPs to talk about the challenges faced by care-experienced young people across the UK. Support #HomeOfOurOwn :
www.instagram.com/reel/DLILR6P... 🇺🇦 #Ukraine #news #video #POW #war #surgery #crime #doctor #body #WarCrimes #soldier #world #russia #captivity
May 28, 2026 News Update with Cael Maslin - Watch CFTK-TV News weeknights at 5, 6, 6:30 & 11 pm. #TerraceBC, #northwestbc, #news, #Kitimat, #PrinceRupert, #Smithers, #BC, #BritishColumbia, #localnews, #cftktv
Ich bin gleich wieder LIVE! 💜 Hilfst du mir, meine Schwester Yonah zu finden? 👀✨️ Ich hab das Gefühl, wir sind nah dran~ 😈 twitch.tv/NinTacchi 👿 #GERVtuber #Vtuber #twitch #streamergirl #gaming #nier #nierreplicant
Somebody has created a GOING HOME PARTY SIGN UP SHEET to CELEBRATE when Donald J. Trump kicks the bucket. The Internet does NOT give a FUCK about shit! 😂😂😂 #WhereDoWeSign😒
Feuer im Kosher Kingdom Supermarkt, Golders Green, London. Die Brandursache wäre laut Feuerwehr bisher unbekannt.
Support your liver. Feel lighter. Stay energized 💚✨ The Liver Support Capsules are designed to help your body’s natural detox process—so you can feel refreshed, balanced, and at your best every day 🌿 visit summitborne.com
Campo troupial bird endemic to Northeastern Brazil. Known for their striking sounds and mimicry.
Joseph Schow is asked if the UCP are monitoring potential impacts of the separation debate on Alberta's economy. He replies by saying the federal Liberals and NDP started the seperatist conversation, and they are reponsible for it continuing.
A boy is playing the accordion and performing the Ukrainian song “How Could One Not Love You, My Kyiv” near the shopping mall in Lukianivka that was destroyed in a Russian attack on May 24, while raising money for the Ukrainian military. #Ukraine is unbreakable. Video: Telegram / Реальний Київ
Always lovely to hit the parkrun finishing funnel, and even lovelier today with parkrun founder Paul Sinton-Hewitt as marshall at Worthing #parkrun #loveparkrun #worthing #DFYB #running #saturdaymotivation
I wish more people knew that you can just ask.😉 The worst thing that can happen, is that they say ‘No’… #Negotiations #Communications #Resiliency #Risk #Sales #Strategy #SauderStrategy🗺️
Cloud's mom has got it goin' on. 😳 ➡️ www.twitch.tv/yaboiedgee #Vclip #VTok #VTuberClips #TwitchClip #babiniku #VTuber #ENVTuber #Vsky #FinalFantasy #FFVII #FF7
#WDEFNews12 Time Saver Traffic: Multi-Vehicle Crash reported Interstate 24 EB in Hamilton County - near MILE MARKER 179.2 EB right shoulder blocked. Site in clean-up mode. Backed up traffic will still be a problem.
Staakt het vuren...sure... Libanon. Pissrael heeft al c.a 400 dorpen en nederzettingen met de grond gelijk gemaakt tijdens deze cease fire
Is Thelma Schoonmaker the greatest film editor ever? 🎞️ 🤩 We revisit her interview on the Take in our International Women's Day special, in partnership with Vanguard 🛡️ 🎥 Celebrating the work of women filmmakers we love 🎬 🎧 Listen pod.fo/e/39b207 📺 Watch www.youtube.com/watch?v=IrXE...
happy three year anniversary to the “rainiest rain show to ever rain show” 🌧️🌧️🌧️
Towers may fall, but bunkers are holding strong💪 🌟 Wishlist the game on Steam : store.steampowered.com/app/3386520/... #IndieGameDev #indiedev #game #RTS #indiegame #voxel #voxelgame
A snippet from this week's Gypceros Podcast episode. #MonsterHunter #MonsterHunterWilds #MHWilds #MonHan #Wilds #Gypceros Find the show: apple podcasts: podcasts.apple.com/us/podcast/m...… Spotify: open.spotify.com/show/2hUq2VJ...… Youtube: youtube.com/playlist?lis...
I’m happy to clarify. President Clinton brought up a conversation he had with Trump in NYC re: Epstein. President Clinton said that Trump told him that he had a falling out with Epstein due to a land dispute. This directly refutes Trump’s claims about why he fell out with Epstein.
"ET OUSMANE, BALLON D'OR !" : Ousmane Dembélé déchaîne la foule en entrant sur la pelouse du Parc des Princes #PSG #Liguedeschampions
GitHub confirms ~3,800 internal repos breached via a poisoned VS Code extension. TeamPCP linked to the attack. 🚨 #cybersecurity Source: https://it.slashdot.org/story/26/05/20/197246/githubs-internal-repos-breached-via-employees-use-of-malicious-vs-code-extension
Sol Ruca says that Oba Femi thinks he can do the Sol Snatcher. I need to see this happen.
A Black Panther party leader in Newark calls out Hasan Piker and other internet blue maga liberal phony "activists" claiming to be "democratic socialists" (Which is fucking contradictory, by the way), for failing to understand what a Proletarian Revolution is supposed to be fighting for.