7) 🧩 Main finding 4. Plug-and-play targeting: LipiGo’s DNA handles act as modular building blocks. Conjugating a white adipocyte–specific aptamer enabled tissue-specific mRNA delivery with enhanced uptake in white adipocytes 🎯

We discovered that the skull bone marrow has direct connections to the brain surface & mirrors brain inflammation, making it a new site for diagnosing & monitoring brain pathologies. Kolabas…Ertürk, Cell (2023): www.cell.com/cell/pdf/S00... Our Tech: www.biorxiv.org/content/10.1... bit.ly/3PQuymm

Our new study shows that SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving long COVID. mRNA vaccines help but cannot stop it🔬🧠🦠🧵Your weekend read👇 @cellpress.bsky.social cell.com/cell-host-mi...

We are introducing LipiGo 🤗 A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...

Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. It reveals obesity-induced changes in facial nerves & body-wide inflammation 👉🧵https://biorxiv.org/content/10.1101/2024.08.18.608300v1.full.pdf

Our recent work in @Nature, MouseMapper uses foundation-model AI, mapping perturbations in mouse body cell-by-cell, revealed unexpected facial nerve damage. Proud to see >75K accesses & >60 news stories in the first week. Paper->> www.nature.com/articles/s41... Next www.biorxiv.org/content/10.6...

Using vDISCO tissue clearing, and a new ultrabright chemical labeling strategy. This work introduces LINCS for rapid, scalable 3D connectivity mapping from single neurons to whole brains, advances for high-throughput circuit mapping. Great work by Rui Lin lab. www.sciencedirect.com/science/arti...

🧠 Does brain aging always mean vessel loss? We found the opposite in some aged brains: maladaptive hypervascularization, linked to cognitive decline and blood-brain barrier damage. Check it out below! www.biorxiv.org/content/10.6...

Excited to share our latest work with Denali Therapeutics as Deep Piction. Using our proprietary clearing & imaging, we’ve mapped the full targeting profile of brain-penetrating transport vehicles (ATVs) in both whole mouse bodies and monkey brains. nature.com/articles/s41...

Our Nature Biotech paper hit 225K+ accesses in 3 months! 🤩 7 first authors from computer science, biology & chemistry prove that great science is teamwork. We combined AI & imaging to visualize single cells across whole organisms. Team synergy > individual brilliance. www.nature.com/articles/s41...

Watch this video for the latest on water main breaks, boil water advisories, water conservation orders and school closings around the Capital Region:

Join us for a provocative discussion as Randy Cramer and Tim Tactical Advisor (Tactical Advisor) reunite to expose the true fallout of World War II M5D Podcast - Be the first to know. Listen on Spotify sptfy.bio/m5d #m5dpodbean

Oil prices are rising on global markets at the start of the week as the U.S. and Iran remain unable to reach an agreement to end the war in the Middle East war and reopen the Strait of Hormuz.

⏪ Rewind: Burnley #lufc

“Having worked in government, you have to realize there’s two pots of money: There’s the people money. There’s the power money.” —DeAnna Hoskins explains #federalfunding Watch the full video: https://jlusa.org/2026/05/04/deanna-hoskins-speaks-on-reentry-issues-at-the-city-club-in-cleveland/

ONLY ONE REASON... why Dems don't want ICE at polling centers. Anyone with a brain stem can figure this out. Illegals can't vote is ICE is securing polls and making sure illegals are not voting. Dems excuse, ''it makes people feel threatened''! BS...it makes ILLEGALS feel threatened. GOOD!!!

My MVP: The Open Door in Gloucester. They serve 2 million meals to low-income residents here in the Sixth — 30% of which are children. Local pantries need our support now more than ever. We need fighters in Congress who will fund SNAP benefits and fight for working families.

Come enjoy the sun 🌞 with me today 🛶 #Chicago

It's SHOWTIME! #AEWDoN ➡️ allelitewrestling.com/aewonppv

A tester made a dungeon where you literally solve math problems! 😄 It'll be available in the demo. Will you play it? 🔢 #indiegames #zelda #nintendo64

Inverted 'X' in the logo? Not the vibe. It's a reminder of the atrocities committed in the name of 'faith.' I live in a supposedly secular country where people ignore how kids are actually raised, yet lose their minds if you choose to remain child-free

Vape shops need to be licensed and better controlled. This #NoSmokingDay I’m calling for more action to tackle vaping. @scottishgreens.org have been clear when it comes to vapes. The Scottish Government must introduce a robust licensing scheme!

Loving FL State Rep Angie Nixon for speaking truth to power! Every single Dem needs to follow her lead. Shout it out & LFG!

#cf97 goal of the day for May 4, 2026: September 30, 2025 - MLS Inter Miami CF 3-5 Chicago Fire - Justin Reynolds 80'

En effet, c’était un classique ce bâton dans le patin de Dobes! 😂😂😂😂 #GoHabsGo

The view from inside Integrity as recovery forces pop open the hatch Credit: Reid Wiseman #Artemis

Caturday Kafka và những ngày mưa Đà Lạt

🚨LIVE‼️Saturday at 5:05PM CT 💫Join the #AEWCollision & #MLWFusion 💥Live Reaction & Review @dedrian91.bsky.social : www.youtube.com/live/LMGtU6s... #aew #mlw #hazuki #stardom

I.C.E. is a domestic terror organization. #Newark #DelaneyHall #ICE

Tae on IG 💜🐻💜 #V #Taehyung #BTS 🔗 www.instagram.com/p/DY9GSv4k5F2/

Kalea Moore starts with the ball 🎯 🩵| #VitalityBlast

🛫 Stop guessing. Start landing! LYNEports makes site selection for air taxis fast & AI-driven: score properties, visualize zoning & airspace, export investor-ready reports, and get top site suggestions with coordinates. Explorer Plan 👉 lyneports.com/pricing

New homeschool curriculum ready for print in the shop! Wonder Garden is an all-in-one for PreK-1st Grade. #homeschool #homeschooling #homeschoolcurriculum #secularhomeschool #homeed #preschool #kindergarten #1stGrade #wondergarden

El consejero Pérez Iglesias analiza la jornada "Faros de Innovación: ecosistema en acción", celebrada hoy en el edificio Olatua, en Getxo, que ha reunido a cerca de 200 agentes de la Red Vasca de Ciencia, Tecnología e Innovación.

TRUMP SUCKS!!! #KINGOFTHEPEDOPHILES #BLUEWAVE26 #resisttheorangeplague

Asked about more Patriots for Ukraine, Hegseth says US manufacturers are ramping up production significantly. "Where we can help Ukraine, we do," he says.

#generalstrike 2026 #goals

📺 El doble de dos carreras de Mark Vientos

Goodnight Blue Sky

As well as freeing them from the devil does she she also relieve them of their money

Bad Bunny vs. personal injury lawyer Richard Jaffe’s Spanish skills…107 days to go! Can he do it? 🏈🇪🇸 ✅ Be sure to follow us for more attorney fun! #BadBunny #SuperBowl2026

Bee has got some moves: 🔊 #AGoodPlace Source: www.reddit.com/r/funny/s/r6...

50 Years Ago Today: An epic bench-clearing brawl breaks out between the #RedSox and #Yankees at Yankee Stadium after Lou Piniella collides with catcher Carlton Fisk! Bill Lee separates his left shoulder in the ensuing skirmish! (May 20, 1976) #OldSchool #MLB #Baseball #History

First Day of Spring Brings Sunshine & Warm Temps to Southeast Texas High pressure will keep conditions warm, dry, and perfect for outdoor activities, making it a great weekend for family fun across Southeast Texas.

At airport lounge waiting for Beijing flight and there is a robot drinks tray because of course there is... #china #hongkong

Trump’s budget makes it clear his priority is NOT American families. CAP's @bbkogan.bsky.social breaks it down:

Friday is #WorldCircusDay so for the Diner on 91.9 WFPK I want you to give me songs that reference any aspect of a circus or carnival IN THE TITLE. (1 x person PLEASE!) Listen for yours starting tomorrow morning at 8 on 91.9 WFPK, lpm.org or the Louisville Public Media app. 🎪🤡

Well is it? Just like my other platform we're gonna re-institute #thirstythursday starting with 🤍Mariella🤍 🤍 #cosplay #HausKas #originalcharacter #catgirl #nekogirl #furry

Der Herr Mini ist gestern in den Regen gekommen. 🐿️💦💦💦🥹 #squirrels #balkonhörnchen #eichhörnchen

Thunder Dragon Plataformas: Arcade Año: 1991 Géneros: Shooter Un juego de disparos para uno o dos jugadores publicado por NMK Co. Ltd. en 1991, desarrollado por NMK Co. Ltd. #ThunderDragon #Arcade #Shooter

Hello Chippewa County! The DPW is holding a Voter Outreach Phone Bank Thursday's from 5:00 - 7:00pm on Zoom. mobilize.us/s/5BD3nY

My birthday is two days away, and I am so excited😁🤞

Make us part of your weekend chill. Relax and tune into the Women Road Warriors empowerment show podcast anywhere you listen to podcasts or @ womenroadwarriors.com. #Weekend #Podcasts #women

More jokes ! #jokesky #funny#comedy#jokes

Israel

After years of propping up Orban, Putin lost the election tonight in Hungary.

you post once, we blast it to 12+ platforms wake up to your content thriving. #socialmediaautomation #contentcreators

@DBR8 : "De Jong és indispensable per a l'entrenador" @victorlozano73 : "Casadó és molt millor que Frenkie de Jong" #OnzeE3 http://Som3cat.video/Onze

Xavi Pascual, abans del partit contra l'UCAM Múrcia: "Hem de comportar-nos com un equip tant si la cosa va bé com si no va bé" https://3cat.cat/esport3/en-directe-barca-ucam-murcia-els-culers-busquen-les-semifinals-al-palau/noticia/3413277/

Softball has a rule that keeps players more honest about being hit by a pitch, a breakdown