Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. It reveals obesity-induced changes in facial nerves & body-wide inflammation 👉🧵 biorxiv.org/content/10.1...

Additionally, we visualized infiltrating CD68-EGFP immune cells linked to chronic inflammation in obesity on the whole-body scale.

Our recent work in @Nature, MouseMapper uses foundation-model AI, mapping perturbations in mouse body cell-by-cell, revealed unexpected facial nerve damage. Proud to see >75K accesses & >60 news stories in the first week. Paper->> www.nature.com/articles/s41... Next www.biorxiv.org/content/10.6...

4 ➡️ Main finding 1. DNA handles protruding from LipiGo enabled functional liver detargeting and strong spleen accumulation. Unlike conventional LNPs that mainly go to the liver, LipiGo redirects mRNA delivery to lymphoid organs.

We discovered that the skull bone marrow has direct connections to the brain surface & mirrors brain inflammation, making it a new site for diagnosing & monitoring brain pathologies. Kolabas…Ertürk, Cell (2023): www.cell.com/cell/pdf/S00... Our Tech: www.biorxiv.org/content/10.1... bit.ly/3PQuymm

Excited to share our latest work with Denali Therapeutics as Deep Piction. Using our proprietary clearing & imaging, we’ve mapped the full targeting profile of brain-penetrating transport vehicles (ATVs) in both whole mouse bodies and monkey brains. nature.com/articles/s41...

We developed MouseMapper AI, a deep learning ensemble for the analysis of whole-body systems, including the nervous and immune systems, to map disease/drug perturbations tissue by tissue, organ by organ, at the cellular level in 3D. biorxiv.org/content/10.1...

7) 🧩 Main finding 4. Plug-and-play targeting: LipiGo’s DNA handles act as modular building blocks. Conjugating a white adipocyte–specific aptamer enabled tissue-specific mRNA delivery with enhanced uptake in white adipocytes 🎯

Today in Nature, we report MouseMapper: foundation-model AI to map disease perturbations across the entire mouse body cell-by-cell. In obesity, it revealed body-wide inflammation & unexpected facial nerve damage. www.nature.com/articles/s41... More at: x.com/erturklab/st...

Our Nature Biotech paper hit 225K+ accesses in 3 months! 🤩 7 first authors from computer science, biology & chemistry prove that great science is teamwork. We combined AI & imaging to visualize single cells across whole organisms. Team synergy > individual brilliance. www.nature.com/articles/s41...

Ed Gallrein: “I’ve been in this race 15 weeks when you take out the holidays.”

Terrifying war crimes exposed! The NYT confirms the Pentagon tested an experimental PRISM missile packed with 180,000 tungsten pellets on an Iranian sports hall. Washington literally used a girls volleyball team as test subjects, massacring 21 civilians. Pure evil!

BREAKING: Tulsi Gabbard to Step Down as Director of National Intelligence

In US politics, elections are dominated by dark money and party gatekeepers. ⚠️  It doesn't have to be this way. 👀 Plug in to the Digital Politics Hub to change how we choose leaders for upcoming midterms. 👉 hub.futureis.org

Break Attention Patterns The Supreme Pontiff of Hinduism Bhagavan Sri Nithyananda Paramashivam reveals the importance of recognizing and breaking patterns that control our attention and behavior. He shares a personal anecdote to illustrate how patterns are formed and how to consciously break them.

"The confusion, causing panic and uncertainty in the process, that is the point of issuing these orders." wzmq19.com/news/360440/... #Trump #MailInBallot #Elections #Vote #Michigan #HandsOffMIVote

Why Iran? Why now? What is the end goal? Americans deserve answers.

Former CIA Officer Joe Kent warns Israel might orchestrate a massive false flag terrorist attack against the US. He confirms the Zionist regime is desperate to keep Washington trapped in the Iran war and will use extreme deception to force compliance.

Unstoppable 🤯

Las tres diferencias de unas gemelas

Get the latest ITIL training videos updated for 2026. Learn ITIL 4 best practices for IT service managemen… → https://coursebond.com/course/itil-training-videos-2026-updated-itil-tutorial-for-beginners-itil-course-information-technology-infrastructure-library-course-simplilearn/

1 of 2 Newark, NJ Delaney Hall: Protesters are outside the facility demanding the release of Martin Soto, the leader that started a hunger & labor strike to protest inhumane conditions. ICE is trying to transfer Martin+ to a different facility; there is no transfer order. @cnn.com @reuters.com

🇨🇦 The Paradox of Digital Sovereignty Canada asked 11,000 people: How should we govern AI? Then used American AI to read the answers. The irony is almost perfect. But it reveals something profound about the future we're building together. New Heliox episode 🎧 www.buzzsprout.com/2405788/epis...

#AEWDON #WrestleSky #MJF #BigHebrew

Credibility Tests ➜ Labour has faced fresh pressure as MPs demand a timetable for Sir Keir Starmer’s departure after electoral losses, and the EU has approved targeted sanctions on settlers and Hamas figures after a long

Ele parecendo um guerreiro antigo, um viking! Pqp simplesmente pisar em mim!!! #BTS_WORLDTOUR_ARIRANG #BTS_WORLDTOUR_ARIRANG_LASVEGAS #BTS_WORLDTOUR_ARIRANG_LASVEGAS_D1

LET’S TALK RECORDS! No. 90 (Redux): LET IT BE by THE REPLACEMENTS Part 2 #letstalkrecords #thereplacements #letitbe #collegerock #punk #punkrock #alternative #alternativerock #vinyl #vinylcollection #vinylcollector #vinylcommunity #vinylrecords #music

I do pay for a housekeeper twice a month. Now all I'm missing is a woman to show up every few weeks dressed in a rubber body suit to run around my house.

A hit and run according to OP who said he heard but didn't see it. West Hollywood. OP: tiktok.notzapata

İstanbul Saint-Joseph Fransız Lisesi öğrencilerinin yıl sonu için düzenlediği dans gösterisi. #BilgiÜniversitesi #FenerbahçeBeko #Sıla #AvBur #THM

Stage view of Ospreay at the end of his match vs Joe @claudiatakesoup.bsky.social #AEW

chaotic and funky music. chaos Still plays the notes btw⚡️ #boombapbeats #boombap #beats #hiphop #sampleflip #music #instrumental #beatmaker #producer #nycmusic #chaos

Coleman Hughes reflects on how the moral frameworks forged in the fight for racial equality are now projected onto global conflicts, flattening history, intent and context in the process, and obscuring more than they reveal.

Protests work with the support of the community. Lawrence, Kansas! #Resist #Protest #LFK

They said “keep politics out of games” so we made an RPG where politics -is- the main gameplay mechanic. #indiegame #pcgaming #gamedev

Now imagine that’s your child separated from her loved ones. She’s braver, more mature, and intelligent than this entire administration!

‘ISRAEL’ KILLS 6 PEOPLE AND INJURES 34 SEMITIC PALESTINIANS IN GAZA, OCCUPIED PALESTINE ON FIRST DAY OF EID. ZERO HEADLINES FROM WESTERN MEDIA SO FAR. #EndIsraeliTerrorism

💥City of Rasslin💥 @dedrian91.bsky.social #powerrankings 🔋 for the week of May 11-17 2026 💥Watch City of Rasslin: youtube.com/@cityofrassl... #aew #roh #wwe #revpro #darbyallin #athena #gunther

Sigh ... obligatory hashtags ... #PrecautionaryPrincipleFFS #PreventionBetterThanCure #Wear≥FFP2RespiratorsNotMasks #NoFalseEquivalence #NameAndNormalise ... and just supply them ... OK? And show them this 1:19 video ...

Working on an AOE Slam Attack that can only be triggered in the air #gamedev #indiedev #gameart #animation3d #MAYA

Jason Anavitarte can't read. He thinks an indictment is equivalent to guilt and that a paid informant spying on a gate group is the same as a member of a hate group.

Lavis dinner hosted by senior London journalist Asad Nawaz in honor of friends. لندن کے سینئر صحافی اسد نواز کی جانب سے دوستوں کے اعزاز میں دعوت

HEINE HEINE HEINE HEINE HEINE HEINE HEINE HEINE MAN

In 2087, a message from deep space warns Earth a harbinger of doom is hurtling towards our planet. It also outlines a plan to save us, but at what cost? Is it a hoax, or a trap, or will we indeed soon face extinction—unless we agree to the ‘Alliance’s terms? #BookSky #SFF amazon.com/dp/B0F82Y9S7X

👓 𝐀𝐩𝐩𝐥𝐞'𝐬 𝐍𝐄𝐖 𝐀𝐈 𝐒𝐦𝐚𝐫𝐭 𝐆𝐥𝐚𝐬𝐬𝐞𝐬 - 𝐄𝐩. 150 #𝐚𝐩𝐩𝐥𝐞 #𝐚𝐢 #𝐚𝐢𝐠𝐥𝐚𝐬𝐬𝐞𝐬 #𝐚𝐢𝐰𝐞𝐚𝐫𝐚𝐛𝐥𝐞𝐬 Thanks for check out my Short. Want a deeper dive into stories like this? Check out my long-form videos on YouTube: www.youtube.com/@TheBusiness... #business #businessnews #tbbtn #youtube #shorts #reels #tiktoks #vids #fyp

🏗️ A smarter way to build housing: https://go.newamerica.org/affordable-and-market-rate-housing-5 💰 Closing construction funding gaps: https://go.newamerica.org/rules-of-housing-finance-5 🏠 Scaling first-time homebuyer programs: https://go.newamerica.org/first-time-homebuyers-in-high-cost-regions-5

AI IS OUTTA CONTROL - Chet's Andy Rooney Chatbot is going haywire & making very wild claims! Will "The Ol' Beef & Chetter" be able to stop the onslaught of extreme misinformation? BIN Barely Informed News ft @caseblackwell.bsky.social streams M/W/F twitch.tv/caseblackwell + @creamteam.bsky.social

Didn’t Trump say no one watches Jimmy Kimmel? Well @hsgac.senate.gov is spending money in Dallas. It bought two commercial spots this week on @jimmykimmel.com show for its #ICE recruitment. Trump knows Kimmel’s ratings keep going up. @Disney

Khorramshahr missile hits #Israel! #Wikipedia: ¨Iran´s long-rang #Khorramshahr, named after the city of Khorramshahr in #Iran, is a medium-range ballistic missile THAT was tested by Iran in January 2017. With a range between 1,000 and 2,000 km, it can carry a 1,800 kg warhead and is 13 m in length.¨

I need some more Pokémon Concierge!

if one asks a favor of the bog witch sealed in a jar, and she makes the jar, and one later makes themselves loathed to the bog witch, those favors will turn into rot and decay sometimes on far grander scales than anything the bog witch would have thought of doing at the time

Mission Minute is back! This time we’re breaking it down into quick, bite sized episodes focused on our core steps: monitor, evaluate, protect. Hear directly from our team as they define their roles in keeping people and elephants safe across the Mara.

Should children be allowed in first class? #news #travel

I called out Reform's backwards vision on the future of coal. Whilst we fight for green jobs of the future, they call for reopening coal mines and fracking which would devastate our countryside.

Mornin’ my good friend, Dennis😎 Bromeliads & Alocasia ( African mask plant)

Fox News Xpress, 7/10/1998 part 1/2 : 1116s

Certeza absoluta q vcs seguem um bando de gente assim.

This will be an ambitious budget framed by an ambitious government, in difficult and uncertain times.

A wet morning but heaviest rain clearing Northeast now with a mix of sunny spells and scattered heavy showers to follow.

Raven Johnson 1 handed finish #WNBA