Ali Maximilian Erturk
@erturklab
Our recent work in @Nature, MouseMapper uses foundation-model AI, mapping perturbations in mouse body cell-by-cell, revealed unexpected facial nerve damage. Proud to see >75K accesses & >60 news stories in the first week. Paper->> www.nature.com/articles/s41... Next www.biorxiv.org/content/10.6...
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More from Ali Maximilian Erturk
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Our new study shows that SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving lon...
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Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. It reveals obesity-indu...
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We developed MouseMapper AI, a deep learning ensemble for the analysis of whole-body systems, including the nervous and immune systems, to map disease/drug perturbations tissue by...
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Today in Nature, we report MouseMapper: foundation-model AI to map disease perturbations across the entire mouse body cell-by-cell. In obesity, it revealed body-wide inflammation &...
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See our recent @naturebiotech.bsky.social study SCP-Nano in flow! Mapping LNPs, AAVs, and DNA nanostructures to track targeting & unseen toxicity before clinical trials 🤩. Already...
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Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. It reveals obesity-induced changes in facial nerves & body-wide inflammation 👉🧵 biorxiv.org/content/10.1...
Additionally, we visualized infiltrating CD68-EGFP immune cells linked to chronic inflammation in obesity on the whole-body scale.
Excited to share our latest work with Denali Therapeutics as Deep Piction. Using our proprietary clearing & imaging, we’ve mapped the full targeting profile of brain-penetrating transport vehicles (ATVs) in both whole mouse bodies and monkey brains. nature.com/articles/s41...
4 ➡️ Main finding 1. DNA handles protruding from LipiGo enabled functional liver detargeting and strong spleen accumulation. Unlike conventional LNPs that mainly go to the liver, LipiGo redirects mRNA delivery to lymphoid organs.
🧠 Does brain aging always mean vessel loss? We found the opposite in some aged brains: maladaptive hypervascularization, linked to cognitive decline and blood-brain barrier damage. Check it out below! www.biorxiv.org/content/10.6...
Using vDISCO tissue clearing, and a new ultrabright chemical labeling strategy. This work introduces LINCS for rapid, scalable 3D connectivity mapping from single neurons to whole brains, advances for high-throughput circuit mapping. Great work by Rui Lin lab. www.sciencedirect.com/science/arti...
Today in Nature, we report MouseMapper: foundation-model AI to map disease perturbations across the entire mouse body cell-by-cell. In obesity, it revealed body-wide inflammation & unexpected facial nerve damage. www.nature.com/articles/s41... More at: x.com/erturklab/st...
We are introducing LipiGo 🤗 A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...
We discovered that the skull bone marrow has direct connections to the brain surface & mirrors brain inflammation, making it a new site for diagnosing & monitoring brain pathologies. Kolabas…Ertürk, Cell (2023): www.cell.com/cell/pdf/S00... Our Tech: www.biorxiv.org/content/10.1... bit.ly/3PQuymm
Our Nature Biotech paper hit 225K+ accesses in 3 months! 🤩 7 first authors from computer science, biology & chemistry prove that great science is teamwork. We combined AI & imaging to visualize single cells across whole organisms. Team synergy > individual brilliance. www.nature.com/articles/s41...
When you play for the culture, you unite. 🇵🇷 In Deep Dive: Listening to Bad Bunny, historian Jorell Meléndez-Badillo talks about how Bad Bunny amplifies Puerto Rican history and political memory on the Super Bowl stage and beyond. Watch the full Deep Dive on YouTube. youtu.be/YYh1WJ2fEUs?...
Why is health insurance tied to your job at all? Dr. LaVeist challenges a system that shapes who gets care—and who doesn’t. #TheSkinYoureIn
Hiding your prices? AI sends customers to competitors instead 💰 #AISEO #PricingTransparency #PricingStrategy #TrustSignals #ChatGPT #SalesOptimization #DigitalMarketing #ConversionTips
BREAKING NEWS: Universal Studios goes racist and our theme park expert is here to explain why this is a good thing. youtu.be/XCjqMkRO244?...
🐟💸FISH MONEY💸🐟 I voice both fish monster bounty hunting sisters, Girla and Milly, in the CalArts animated short film FISH MONEY by Gen Funes! All power, all chaos 😎🦈 Watch now on YouTube: youtu.be/BEYR3T2pH8k?...
Happy New Year! Time to fulfill your resolutions with some voiceover workshops! 🥳🎙️ Our Anime and Live-Action ADR/Dubbing Workshop is back and stronger than ever in 2026! This one will be on Friday, January 30th, at 4-7 pm PST/7-10 pm EST. Details below!🧵
🎁🎶 We don't want a lot for Christmas...maybe just a wishlist of our #indiegame? 👀👉👈 Stir up chaos and coffee in Spill the Beans, a reverse detective #visualnovel set in a cozy fantasy café! ➡️ bit.ly/spill-the-be... ☕🔎 #wishlistwednesday #gamedev
Nadia is showing off the Mandalorian Voice-Changing Helmet and the Beskar finish is so shiny you can practically use it as a mirror! This full-scale adult replica is packed with detail, featuring over 10 character phrases and a built-in voice changer.
It’s tussock moth caterpillar season again! And in its honor I’m reposting this video from 2024 about “the chunks” aka the horrible rash that they cause. Lol trust me, you don’t want the chunks! #forest #nature #outdoor #outdoors #wild #forester #animal #animals #wildlife #insect #insects #woods
I am proud to nominate Reginald Freeman as our next Minneapolis Fire Chief. Minneapolis aims to be on the cutting edge of emergency response, and Reggie will help us get there, while building on the excellence in service for which our firefighters are known.
On the next episode of A Moment with Erik Fleming! #blacksky #politics #podcast @davideliot.bsky.social
A battle of the giants this week as we welcome two of our biggest vessels - @princesscruise.bsky.social Majestic and @msccruisesofficial.bsky.social Preziosa - on consecutive days, plus first calls of the season from a host of others. @visitbelfast.bsky.social Visit https://bit.ly/4kTti0O
We want to hear what leaseholders think of the Government's plans for commonhold and leasehold reform. Help us decide what changes to recommend to the Government to improve the draft Bill, as @florenceeshalomi.bsky.social explains. Take our survey by 31 March: https://forms.office.com/e/Hj27jXurmA
Wait for it .... 11 seconds and BOOM! Some breathtaking footage from Fuego 🇬🇹 and @boisestate.bsky.social scientists in this great science update on infrasound sensors. eos.org/science-upda...
Breaking news: The Menands fire house on 250 Broadway caught on fire this Sunday afternoon/evening. Stay with CBS6 as we learn more from the chief at 11 p.m. tonight.
F*ck the #UEFA fan zones off. Get down #Thomaswiese from 4pm Wednesday. #Palace on the piss in #Leipzig. #crystalpalace #cpfc #football #soccer #footballnews #footballsupporters #footballfans #footballculture #fyp #bluesky #sport #sports
fucking craziest take on the space colony ark flashback in any official piece of sonic media. that's just facts, i'm afraid
Any and all reporting about the U.S. and Iran coming up with a deal that ignores the third major party in this war is incomplete. #iran #straitofhormuz #foreverwar #middleeast #diplomacy
🗨️"The thing about a democracy is the electoral system is supposed to deliver what the voters want." Instead, looking around councils in England we see some very warped outcomes. But it doesn't have to be this way. In Scotland & Wales, the results better reflect the balance of opinion among voters.
🎁 für KollegInnen beim @carlsenverlag 💃🏻🕺🏻✨ #derkleinemeier #illustration #hamburg #fckafd #fcknzs
𝗪𝗶𝗹𝗹 𝗔𝗜 𝗰𝗵𝗮𝗻𝗴𝗲 𝘂𝗿𝗯𝗮𝗻 𝗺𝗼𝗯𝗶𝗹𝗶𝘁𝘆?🤖 This is the last post of our #CitiesInMotionVI campaign, and we explore #ArtificialIntelligence. We see #cities testing smart solutions, like Geo for Cities or digital Traffic Circulation Plans, while with #LIST we analyse the implications of #AI 🚦 🔗 buff.ly/8CQ9VwA
📵 Putin, like any good dictator, “protects” Moscow by shutting down the Internet for over a week! No bad news, no protests… just $70M in business losses. 👍 You don’t cut Internet if everything’s fine. Putin fears the truth—and the collapse is starting. 👀 #StandWithUkraine #MakeRussiaSmallAgain 🇺🇦
Not very good at Invincible VS, but I’m definitely learning. A couple of choice moments from online 🥹
Killers disguised as UPS workers committed violence in front of a toddler because they’d rather take than go out and get it themselves. Full Episode: https://www.youtube.com/live/zXbeq7XZy6c?si=DnTLoFWh656kmoJT #untraditionalentrepreneur #blindtrust #ups #upskilling #rawtalk #realitycheck
"Enemy infantry becomes fertilizer in the #Lyman direction🔪" #SIGNUM again showing exelent flying skills seeking, hunting and eliminating #ruZZian copter-fodder. [👇👀💪💙💛✊ 🇺🇦✌️]
Tommaso Ciampa finding out the hard way you empty the can before you look for plunder as it is ANYTHING GOES between Ciampa and Mark Briscoe! #AEWDynamite is LIVE on TBS and HBO Max
Not what your FPPC Form 750 says, Tom California Fair Political Practices Commission — a public document to disclose personal financial interests in order to ensure that public officials make governmental decisions in the best interest of the public rather than enhancing their personal finances.
Detective Hana is closing in on the truth in a city that never sleeps. When the informant disappears into the shadows, the hunt truly begins. Check the link in my bio to follow the full investigation. #cyberpunk #noir #storytelling #detective
Der kleine Staubsauger war gerade da. 🌰🐿️😍 #squirrels #balkonhörnchen #eichhörnchen
When Racists Are Given the Powers of State, Everybody Dies😂 #ASE — Not Just Black People No debate.😴💤 theorionblogown.blogspot.com/2026/01/when... Grok on DNA-Coded Shapeshifting Gadgets😴💤 theorionblogown.blogspot.com/2025/08/dna-... #GENOCIDE #LOOSH #NYC #Aus #Mecca #Berlin #Bro #Vienna #Warsaw
In four years, Israel fell 30 points in the press freedom index. And this year’s ranking is the lowest it’s ever been, reflecting censorship, political interference, and killing of journalists in Gaza, the West Bank and Lebanon.
Tired of your Marketplace health premiums skyrocketing? Political and government instability has caused major increases — but EZ Access Insurance has the solution: Get affordable nationwide coverage. 📞 Call: 833-726-7467 🔗 Enroll Now: https://www1.impacthealthsharing.com/?referral_id=08651770
we’re honored to continue building something special with Coach Charles Lee 🐝 Original post
ENRAGED TO ENGAGED ✊ Turn energy into action at our April Members’ Meetup & Civic Action Fair. Find your role in the fight for democracy, and support our Inasmuch Ministry donation drive. 🌊 🗓️ 4/14 | 5:30–8:30 PM 📍 Psi Ote Upper Pavilion #IndivisibleNEI #FortWayne #CivicAction
January has been anything but dry, and Ardingly Reservoir is now full. Yet Mid Sussex residents are still under a hosepipe ban. Please sign my petition calling for the hosepipe ban to be lifted. South East Water need to lift the ban now! www.midsussexlibdems.org.uk/campaigns/en...
Okay... So... I managed to get most of the important books out today... I...have to donate the ones I didn't want today... Get MOST of the fragile small furniture out... And rent a truck for the large stuff tomorrow. A-and I think I'm sick and my back HELLA hurts. Ow...April has been awful
Sept 25 Talk: “Why Privacy Matters: Who’s at Risk in the Digital Age” 🔒 Your data isn’t just yours — who’s watching, tracking, and selling it matters. Full Disinfo Detox episodes in the comments 👇
A clip from my recent set in the Trans Christian Andersen & Friends new trans & queer comics showcase, as part of the Sydney Comedy Festival (yes, I am going to be repeatedly telling people I've performed at the festival).
Ranking Stafox characters by hotness. Do you agree with us?! ⬇️ #starfox #nintendo #rankthecharacters #gaming #starfoxadventures
Drivers on Burnt Store Road near the Charlotte County line will encounter construction trucks, barricades and signs for the next several months as Lee County works to improve safety on the road. More: https://www.gulfcoastnewsnow.com/article/construction-burnt-store-road-safety-cape-coral/71463978
Massive eruption on the E limb! Another one (if you didn't see it yet) @loveon9.bsky.social Jure Atanackov x.com/JAtanackov/s... Videos from Helioviewer and www.ssec.wisc.edu/data/geo/#/a...