Ali Maximilian Erturk
@erturklab
Excited to share our latest work with Denali Therapeutics as Deep Piction. Using our proprietary clearing & imaging, we’ve mapped the full targeting profile of brain-penetrating transport vehicles (ATVs) in both whole mouse bodies and monkey brains. nature.com/articles/s41...
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More from Ali Maximilian Erturk
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Our new study shows that SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving lon...
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Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. It reveals obesity-indu...
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We developed MouseMapper AI, a deep learning ensemble for the analysis of whole-body systems, including the nervous and immune systems, to map disease/drug perturbations tissue by...
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See our recent @naturebiotech.bsky.social study SCP-Nano in flow! Mapping LNPs, AAVs, and DNA nanostructures to track targeting & unseen toxicity before clinical trials 🤩. Already...
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Today in Nature, we report MouseMapper: foundation-model AI to map disease perturbations across the entire mouse body cell-by-cell. In obesity, it revealed body-wide inflammation &...
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7) 🧩 Main finding 4. Plug-and-play targeting: LipiGo’s DNA handles act as modular building blocks. Conjugating a white adipocyte–specific aptamer enabled tissue-specific mRNA delivery with enhanced uptake in white adipocytes 🎯
Today in Nature, we report MouseMapper: foundation-model AI to map disease perturbations across the entire mouse body cell-by-cell. In obesity, it revealed body-wide inflammation & unexpected facial nerve damage. www.nature.com/articles/s41... More at: x.com/erturklab/st...
Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. It reveals obesity-induced changes in facial nerves & body-wide inflammation 👉🧵https://biorxiv.org/content/10.1101/2024.08.18.608300v1.full.pdf
We discovered that the skull bone marrow has direct connections to the brain surface & mirrors brain inflammation, making it a new site for diagnosing & monitoring brain pathologies. Kolabas…Ertürk, Cell (2023): www.cell.com/cell/pdf/S00... Our Tech: www.biorxiv.org/content/10.1... bit.ly/3PQuymm
Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. It reveals obesity-induced changes in facial nerves & body-wide inflammation 👉🧵 biorxiv.org/content/10.1...
To see how obesity affects the body, we used vDISCO clearing and imaging to visualize the peripheral nervous system in both lean and obese mice.
🧠 Does brain aging always mean vessel loss? We found the opposite in some aged brains: maladaptive hypervascularization, linked to cognitive decline and blood-brain barrier damage. Check it out below! www.biorxiv.org/content/10.6...
Our recent work in @Nature, MouseMapper uses foundation-model AI, mapping perturbations in mouse body cell-by-cell, revealed unexpected facial nerve damage. Proud to see >75K accesses & >60 news stories in the first week. Paper->> www.nature.com/articles/s41... Next www.biorxiv.org/content/10.6...
Additionally, we visualized infiltrating CD68-EGFP immune cells linked to chronic inflammation in obesity on the whole-body scale.
Our Nature Biotech paper hit 225K+ accesses in 3 months! 🤩 7 first authors from computer science, biology & chemistry prove that great science is teamwork. We combined AI & imaging to visualize single cells across whole organisms. Team synergy > individual brilliance. www.nature.com/articles/s41...
Delivering #BSL Interpreting Services or other communication services in the UK? 🙌 Think it could be done better? Us too! Join our co-op and be part of change! buff.ly/2V26cKW
BREAKING: Alleged White House Correspondents' Dinner attacker identified as Cole Allen, a mechanical engineer from Torrance, California. MS NOW's Ken Dilanian has the latest.
ALL our Oils are 100% EO fragrances. These oils are perfect for use in cars, diffusers, humidifiers, homes, offices, ect. GREAT FOR SMOKERS using a humidifier, guarantee to kill smoke scent. meltsbysusanstore.etsy.com ebay.com/str/susancan...
🌹💔 Ukraine Russia War | Ru Pov: People Carry Flowers to Site of Tragedy in Starobilsk | RCF NSFW & Premium Content: https://patreon.com/RealCombatFootage Odysee: https://odysee.com/@RCF #RealCombatFootage #RCF #War #Military #WorldNews #BreakingNews #UkraineRussiaWar
The Lee County Sheriff's Office arrested four teenagers who are accused of beating and choking a boy unconscious at an Estero house party. More: https://www.gulfcoastnewsnow.com/article/teens-arrest-beat-boy-fight-house-party-florida/71341362
Together, we step into InterLink 5.0not just an idea, but a real experience. Where innovation meets people, full of energy and possibility. 🔥✨ #InterLink #ITLG #ITL
Creese moss = Einstein Visa walk me through that one and talk really slow like I don’t know what Einstein is
One internship can completely change a career path. From healthcare market research to agency life and media buying, this journey highlights how curiosity and mentorship often shape the future more than rigid career plans. #MarketingCareer #HealthcareMarketing #MediaBuying
New song 🎧 : Jadis’ Gift is a reminder that not all gifts are what they seem. Out February 14—pre-save now. distrokid.com/hyperfollow/...
The white van has just overtaken & is stopped because of oncoming truck. I'm leaving space if they need to reverse. So the SUV thinks it's a good idea to then overtake to fill that space. Both know before overtaking where they're going next. Both delaying me as I'll fit through on bike before them.
No marketing on sundays so here's 30 sec of pure gameplay of my indie game 🫡
Tod's always been interested in longbows - even if they have some downsides 🏹 #todsworkshop
4/10/26 Where are the nukes? Witkoff said Iran had 11 nukes being made in three months. Where are they? Have they been confirmed to be destroyed? #news #politics #currentevents
Want to see your name — or a loved one's — in the pages of your next favorite book? Place a bid in PEN America's Character Naming Auction at: pen.org/2026-character-auction. Auction ends May 15 at 5pm ET. All proceeds support our new Author Safety Program.
What is the difference between B level and C level in English? 📊📘 Discover the key differences between B-level and C-level English, including fluency, vocabulary range, 🚀 Take Your English to the Next Level: 👉 englishmasteryhub.com #LearnEnglish #EnglishLevels #B2toC1 #ImproveEnglish
newsを更新しました! HARRISONS ‘SEA BREEZE’ fibonacci.tokyo.jp/?p=15898 #墨田区 #鐘ヶ淵 #フィボナッチ紳士洋品店 #オーダースーツ #harrisons
Ari Abdul reveals how she saves money while on tour... #ariabdul #digitaltourbus #businvaders #tourvan #tourlife
Why is dating more difficult - for successful women? Relationship Advice / Female Entrepreneur Tips / Dating Strategy / Women In Business / Love And Success
En 1+1 dimensions (une dimension spatiale, une temporelle) et sans matière, la relativité générale devient triviale. Le tenseur d’Einstein est identiquement nul, il n'y a pas de degrés de liberté gravitationnels propagatifs (il n'y a pas d'ondes gravitationnelles), pas de gravitons.
#ResidentEvilRequiem #cosplay | Leon Axe Holder Adjustments [GER] Der Axthalter, den ich gekauft hatte, war leider zu klein für meine selbstgebaute Schaumstoffaxt 😒. Deshalb musste ich ihn mit Schaumstoffresten, Pappe und Epoxidharz etwas verbreitern. Und ein paar Magnete kamen auch noch dazu 😃
“Else Marie Pade (b. 1924, d. 2016), a path-maker of musique concrète and European electronic music. Over a career spanning multiple decades, Pade approached sound as a medium of electronically generated tunes, exploring intensities, multitudes, and dissonance.” www.kw-berlin.de/en/exhibitio...
The #FoodRenaissance continues weight scale be DAMNED 😂🤣 !!! 🥢🥢♥️♥️♥️♥️ #eatingliketheresnotomorrow #foodieking #yumyumtime #letseat
Hospice is a calling, guided by empathy, compassion and a deep belief in the privilege of caring for someone in their final months or hours of life.
we are seven (#RileyGreene) strikeouts into the season and training in a game we played shoddy defense so we could fall behind #Tigers let's go - - - > get rolling
The Jones Act makes shipping within the United States more expensive — think of it as a tax on domestic commerce, explains Cato's Colin Grabow. Learn more about one of America's most costly protectionist laws on our YouTube channel: https://ow.ly/M5RM50Z3gpr
Yuan Meng (Zoo Beauval) enjoyed a special snack and played in his pool on Christmas~from 12/25/25. No recent updates on le petit prince...hope he's doing okay.🧸 [Cr. 宠物物语馆/Weibo]
BASH: There are questions about the private funding for Freedom 250. It's not transparent. Should the public show know? BURGUM: Transparency is always a good thing. I work for the president I think i most transparent ever BASH: So you'll make the donors public? BURGUM: It's not about the donors
Are you having a heckin' week, #gamer fam? No need to fret, #Wednesday means it is half gone! Also means it is #WICKED WEDNESDAY WITH WING~! twitch.tv/awingedshield Jumping back in #GhostwireTokyo today! Come slap some #ghosties and #spirits with me! #Eldenwood #VTuber #ENVTuber #neko
https://francais.rt.com/ Le chef du bureau de #Zelensky a déclaré qu’il avait ordonné de mettre fin à la guerre dès que possible, et qu’il était possible de parvenir à un accord avec la #Russie. Comment évaluez-vous cette déclaration et quand les
13/13 Last one for now, from St Petersburg, giving a further clue to locals' anger in Russia's second biggest city. The attack continues. No air defence - Ukraine's drones just swooping low over tower blocks. A LOT of Russian swearing in this clip.
AEW DYNAMITE LIVE STREAM Tonight - 745PM ET LIVE ON YOUTUBE/Twitch The most unscripted, uncensored & unbiased wrestling coverage! Even the wrestlers are watching! We are the Wrasslin’ fans united! What will happen? Link Above! Don’t Miss Out!! #WFU #W4LN #aew #aewdon #aewforbiddendoor
Hit that jawn and send the boys to Philly for the 2026 All-Star Game! #VoteMariners 🌟 http://Mariners.com/Vote 🌟
#Zelensky in open letter to #Putin proposes face-to-face Confrontation😍 www.france24.com/en/europe/20... Total #War 🔱 Story: Vishnu and the Demons - the Slaying of Madhu and Kaitabha. theorionblogown.blogspot.com/2026/04/stor... #London #Paris #Berlin #Brussels #Madrid #Rome #Vienna #Moscow #Kyiv
Say goodbye to weeds with WeedWarden, the autonomous robot transforming residential lawns by eliminating unwanted plants with up to 90% less herbicide use.
📊 2026-06-04 • SpaceX: June 2: T-2 to IPO Roadshow — Starlink 12-26 Scrubbed; $6.45B Space Force Week; S-1/A on SEC EDGAR • Battery Revolution: Volkswagen Launches Two More Affordable EVs — Widening EV Access as Global Transition Accelerates • Artemis II: ARTEMIS III CREW REVEAL… 🔗 watchboard.dev
Freak Athlete Hyper Pro Leg Developer & Upper Body Kit Preview Lower and upper body with the same attachment #homegym #garagegym #freakathlete
🎬 Anna Faris says she felt love from Scary Movie fans “for many years, but not from the industry.” 📸 credit: @Variety 👉 N Crowd, do you think Anna Faris deserved more recognition? #AnnaFaris #ScaryMovie